Overview of Chosen Chemical Compounds and Intermediates
Overview of Chosen Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the procedure of numerous myeloma. Its synthesis or review is vital for guaranteeing the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound during the synthesis of imatinib, a drug that targets specific types of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the output method and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to treat breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Facet CAS NO. 134790-39-9 Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and tiny mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have different apps, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind two diabetic issues that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of various gluconic acid derivatives, which might be used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A 2-deoxy-2 precursor in the synthesis of canagliflozin, a medication applied to deal with sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).